Virology 2015 Lecture #2 - The Infectious Cycle

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The infectious cycle is the name for the entire sequence of events from virus binding to cells to release of new progeny virions. In this lecture we define the infectious cycle, and enumerate how to study it. We cover titration of infectious viruses by plaque assay, multiplicity of infection, and the particle to pfu ratio. We also discuss physical methods for detecting viruses including hemagglutination, polymerase chain reaction, and deep, high-throughput sequencing.

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